CHED 428 |
| Formation and control of carbon-carbon bonds are an essential part of organic synthesis. The ability to also dictate regioselectivity during these formations is an important step in formation of natural products and synthetic templates. Indium metal has historically shown to add preferentially to unsaturated carbonyl moieties in a 1,2- in preference to a 1,4-addition pathway. Studies in our lab have shown that a 1,2-addition to propargyl aldehydes followed by an in situ oxy-Cope rearrangement allows synthetic flexibility to form either the 1,2- or the “1,4”-addition product. The poster will describe the mechanistic and synthetic studies behind this reaction.
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Undergraduate Research Poster Session: Organic Chemistry
11:15 AM-1:15 PM, Monday, 14 March 2005 Convention Center -- Hall D, Poster
Division of Chemical Education |
