Carbanion-mediated strategies for synthetic aromatic chemistry

ORGN 251

Victor Snieckus, snieckus@chem.queensu.ca, Queen's University, Kingston, ON K7L 3N6, Canada
Carbanion-mediated Strategies for Synthetic Aromatic Chemistry.

The simple link between the Directed ortho Metalation (DoM) reactions and the rich cross coupling chemistry of B, Mg, and Zn (1) and the enabling Directed remote Metalation chemistry (2) has allowed the development of new regiospecific strategies in aromatic synthesis.  Recent results from our laboratories will be described.