ORGN 849 |
| Microarrays have been demonstrated to be powerful tools for the detection and evaluation of activity of hydrolytic enzymes. They allow a sensitive detection of enzymes with only tiny amounts of a sample. The data from substrate arrays furthermore can be used to functionally differentiate similar enzymes on the basis of their reactivity profiles, or fingerprints.We have developed a new substrate microarray-based strategy for detecting lipolytic enzymes. This system can be easily adapted to other classes of hydrolytic enzymes. The detection is made by long wavelength fluorescence reading and is compatible with standard DNA-microarray scanners.
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Asymmetric Reactions, Molecular Recognition, Self Assembly, Bioorganic Chemistry, Process R&D
8:00 PM-10:00 PM, Wednesday, 16 March 2005 Convention Center -- Hall D, Poster
Sci-Mix
Division of Organic Chemistry |
