Development of transition metal catalysts for organic synthesis

ORGN 393

F. Dean Toste, fdtoste@berkeley.edu, Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720-1460
The development of new classes of robust catalysts, with broad applicability, that are capable of promoting reactions in “open-flasks” – without the need for exclusion of air and moisture – will be discussed. These catalysts can be divided into two classes: a) high oxidation-state transition-metal complexes, particularly those based on rhenium(+5) and vanadium(+5) and b) transition-metal complexes that are stable in low oxidation-states, for example those derived from gold(+1).