ORGN 742 |
| Biological systems exhibit exquisite selectivity in the recognition process. Preorganization and cooperativeness of functional groups often play a crucial role in biological reactions. The inherent preorgnization and synthetic modularity of resorcin[4]arene cavitands make them promising building blocks for constructing multifunctional enzyme models. There has been increasing interest in developing biologically active synthetic receptors or enzyme mimics based on resorcin[4]arene cavitand. We report here the synthesis and characterization of a resorcin[4]arene cavitand-adenosine nucleoside hybrid. To our knowledge, this is the first example of a hybrid compound between resorcin[4]arene cavitand and adenosine nucleoside.
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Asymmetric Reactions, Molecular Recognition, Self Assembly, Bioorganic Chemistry, Process R&D
8:00 PM-10:00 PM, Wednesday, 16 March 2005 Convention Center -- Hall D, Poster
Division of Organic Chemistry |
