Intramolecular Morita-Baylis-Hillman cycloalkylation reactions

ORGN 619

Kimberly A. Seibert, brookovr@chem.fsu.edu, Thomas F. N. Haxell, thaxell@chem.fsu.edu, and Marie E. Krafft, mek@chem.fsu.edu. Department of Chemistry, Florida State University, Tallahassee, FL 32306-4390
The organomediated Morita-Baylis-Hillman reaction couples aldehydes with the alpha-carbon of enones. We have advanced the synthetic utility of the process to include reactions with alkyl halides that proceed in excellent yields.

 

New Reactions and Methodology
8:00 AM-12:00 PM, Wednesday, 16 March 2005 Convention Center -- Ballroom 20 C-D, Oral

Division of Organic Chemistry

The 229th ACS National Meeting, in San Diego, CA, March 13-17, 2005