Copper-catalyzed synthesis of vinyl sulfides

ORGN 103

D. Venkataraman, dv@chem.umass.edu1, Craig G. Bates, cbates@chem.umass.edu2, Pranorm Saejueng, psaejuen@chem.umass.edu2, and Michael Q. Doherty, mqdohert@student.umass.edu2. (1) Department of Chemistry, University of Massachusetts Amherst, 710 North Pleasant St, Amherst, MA 01003, (2) Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003
We report a method for the synthesis of vinyl sulfides using the soluble copper(I)-catalyst [Cu(phen)(PPh3)2]NO3. The desired vinyl sulfides are obtained in good to excellent yields with retention of stereochemistry. This protocol tolerates a wide variety of functional groups or substrates, is palladium-free and does not require the use of expensive or air-sensitive additives.

 

Heterocycles, Aromatics, Materials, Devices, Switches, Combinatorial Chemistry, Metal-Mediated Reactions
8:00 PM-10:00 PM, Sunday, 13 March 2005 Convention Center -- Hall D, Poster

Sci-Mix
8:00 PM-10:00 PM, Monday, 14 March 2005 Convention Center -- Sails Pavilion, Sci-Mix

Division of Organic Chemistry

The 229th ACS National Meeting, in San Diego, CA, March 13-17, 2005