ORGN 398 |
| This lecture will summarize the development of a new approach to (i) controlling chemical reactivity and (ii) discovering functional synthetic molecules that is based on Nature's approaches to biosynthesis and discovery. Insights into the nature of DNA-templated synthesis (DTS) will be presented, as well as the integration of these insights into the development of multistep small-molecule syntheses programmed by DNA, reaction modes made possible by DTS, DNA-templated small-molecule library synthesis, and a DTS-based approach to the discovery of new chemical reactions. Our findings enable the discovery of functional synthetic molecules and new chemical reactions to benefit from powerful processes such as translation, selection, and amplification previously available only to biological macromolecules. |
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Ronald Breslow Award for Achievement in Biomimetic Chemistry
1:40 PM-5:05 PM, Tuesday, 15 March 2005 Convention Center -- Ballroom 20 C-D, Oral
Division of Organic Chemistry |