ORGN 618 |
| The Morita–Baylis–Hillman reaction is a three component reaction in which Michael acceptors are coupled at the alpha-position to electrophilic carbonyl compounds under the influence of a nucleophilic catalyst. Herein, we have extended this method to include intramolecular examples bearing electrophilic allylic leaving groups which provide a facile, high yielding straightforward synthesis of densely functionalized cyclic molecules.
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New Reactions and Methodology
8:00 AM-12:00 PM, Wednesday, 16 March 2005 Convention Center -- Ballroom 20 C-D, Oral
Division of Organic Chemistry |
