ORGN 266 |
| Catalytic processes that form functionalised cyclic molecules represent a key transformation for synthetic organic chemistry. Our recent studies have identified the utility of ammonium ylides for carbon-carbon bond formation and here we describe the development of the first enantioselective organocatalytic intramolecular cyclopropanation reaction to form [n.1.0]-bicycloalkanes. This powerful new process effects the formation of three stereocenters, two carbon-carbon bonds and two ring systems in a single transformation from linear achiral starting material.
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Asymmetric Reactions and Syntheses
8:00 AM-12:00 PM, Monday, 14 March 2005 Convention Center -- Room 11A, Oral
Division of Organic Chemistry |
