New metabolites from the caribbean gorgonian coral Pseudopterogorgia bipinnata

ORGN 163

Claudia A. Ospina, clospina69@hotmail.com and Abimael D. Rodríguez, arodrig@cnnet.clu.edu. Department of Chemistry, University of Puerto Rico, P.O. Box 23346, San Juan, PR 00931-3346
Six new undescribed diterpenes have been isolated from Colombian specimens of the gorgonian octocoral Pseudopterogorgia bipinnata. Compounds 1 - 4 are representatives of the pseudopterane family and are characterized by the presence of a 3(2H)-furanone. The remaining metabolites are members of a new cembrane-derived diterpene family possesing a novel spiro [9.4] tetradecane carbon framework. Their chemical structures and relative stereochemistry were elucidated by NMR and MS experiments. The isolation, structure determination and biological activity of these metabolites will be discussed in detail.


 


 

Heterocycles, Aromatics, Materials, Devices, Switches, Combinatorial Chemistry, Metal-Mediated Reactions
8:00 PM-10:00 PM, Sunday, 13 March 2005 Convention Center -- Hall D, Poster

Division of Organic Chemistry

The 229th ACS National Meeting, in San Diego, CA, March 13-17, 2005