Convenient microwave-assisted organic synthesis of 1,3,5-triarylobenzenes by cyclotrimerization of in situ formed enaminones

ORGN 173

Ronny Lundin, ronny.lundin@biotage.se and Panagiotis Ioannidis, panagiotis.ioannidis@biotage.se. Biotage Sweden AB, Kungsgatan 76, Uppsala, SE-753 18, Sweden
A microwave-assisted one-pot procedure for the two-step synthesis of 1,3,5-triarylobenzenes from aryl ketones is described. The final products were purified by use of an automated flash chromatography system.