Preparation and functionalization of enantiopure secondary boronic esters

ORGN 786

Wesley J. Moran, wesley.moran@manchester.ac.uk, School of Chemistry, The University of Manchester, Manchester, M13 9PL, United Kingdom and James P. Morken, Department of Chemistry, University of North Carolina at Chapel Hill, Venable and Kenan Laboratories, Chapel Hill, NC 27599-3290.
Hydrogenation of vinyl boronates has received little attention in the chemical literature; however considering the synthetic utility of the resulting alkyl carbon-boron bond a convenient asymmetric preparation would be highly desirable. This poster reveals conditions for the catalytic, asymmetric hydrogenation of 1,1-disubstituted vinyl boronic pinacol esters and the functionalization of the resulting secondary carbon-boron bond.

 

Asymmetric Reactions, Molecular Recognition, Self Assembly, Bioorganic Chemistry, Process R&D
8:00 PM-10:00 PM, Wednesday, 16 March 2005 Convention Center -- Hall D, Poster

Division of Organic Chemistry

The 229th ACS National Meeting, in San Diego, CA, March 13-17, 2005