ORGN 148 |
| N-Alkylpyridinum salts are compounds that have found utility as phase transfer catalysts and in drug delivery processes. They are also known to possess antiseptic properties. We report the synthesis of a homologous series of surface active amphiphilic N-alkylpyridinium salts. They are functionalized with a monodisperse oxyethylene oligomeric chain which regulates the hydrophilic-hydrophobic balance and water solubility. The series includes molecules depicted below, where m = 6, 8 and n = 1, 2, 3, 4. The design, synthesis, purification and characterization of this series of compounds will be described.
|
|
Heterocycles, Aromatics, Materials, Devices, Switches, Combinatorial Chemistry, Metal-Mediated Reactions
8:00 PM-10:00 PM, Sunday, 13 March 2005 Convention Center -- Hall D, Poster
Division of Organic Chemistry |
