ORGN 33 |
| Selectivity in organic chemistry is dominated by the intrinsic reactivity of the substrate (aldehydes reduce more readily than ketones) but biochemical selectivity is dominated by the geometry of the enzyme/substrate complex. In biomimetic systems we have achieved such geometrically controlled selectivity, both in catalytic processes and in reactions where hydrophobic effects control the orientation of reagents next to substrates. Progress and prospects in this field will be described. |
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Current Aspects of Synthetic Organic Chemistry
1:10 PM-5:00 PM, Sunday, 13 March 2005 Convention Center -- Ballroom 20A-B, Oral
Division of Organic Chemistry |