Glycosylation of thiols is an attractive area of research because of the biological activities of S-glycosides.  Our ongoing studies of metal-mediated chemical transformations have demonstrated various indium-induced reactions.  During the course of study, we have discovered indium metal-mediated stereospecific synthesis of b-glycosides using bromosugar and thiols.  This can be explained by a SN₂-type reaction of thiol with bromosugar.  However, the role of indium in promoting the formation of b-glycosides with 2-acetoxy and 2-deoxy bromosugar is not properly understood.