ORGNThursday, August 26, 2004

8:00 AM-12:00 PM Pennsylvania Convention Center -- 201A, Oral
Proteins, Peptides, and Amino Acids
Presiding:Richard Cheng
8:00 AM Synthesis of quaternary amino acids bearing an alpha-(2'Z)-fluorovinyl branch: Potential PLP enzyme inactivators
David B. Berkowitz, Roberto de la Salud-Bea, Wan Jin Jahng
8:20 AM Electronic control of peptide cis-trans isomerism
Neal J. Zondlo, Krista M. Thomas, Alaina M. Brown
8:40 AM Preferred peptide backbone conformations in the unfolded state revealed by the structure analysis of alanine based (AXA) tripeptides in aqueous solution
Reinhard Schweitzer-Stenner, Fatma Eker, Kai Griebenow, Xiaolin Cao
9:00 AM Stable conformations of dipeptides in aqueous solution probed by electronic circular dichroism spectroscopy
Andrew Hagarman, Tom Measey, Fatma Eker, Kai Griebenow, Reinhard Schweitzer-Stenner
9:20 AM Alanine dipeptides investigated by FTIR for a quantitative understanding of side chain contributions to the amide I band
Tom Measey, Andrew Hagarman, Fatma Eker, Kai Griebenow, Reinhard Schweitzer-Stenner
9:40 AM The amyloid β peptide segment Aβ1-28 adopts a stable helix conformation at TFE/H20 mixture and alkaline pD
Fatma Eker, Kai Griebenow, Reinhard Schweitzer-Stenner
10:00 AM A synthetic approach to water soluble nanoscale molecules with controlled structures
Christian E. Schafmeister, Stephen A. Habay, Christopher G. Levins, Paul M. Morgan, Gregory H. Bird
10:20 AM Hydrogen bond surrogate approach for the synthesis of short α-helical peptides
Paramjit S. Arora
10:40 AM Strategies for the isoform-selective regulation of protein function with small molecules
Peter J. Belshaw, Brock F. Binkowski, Russel A. Miller, Konstantin Levitsky, Christopher J. Ciolli, Melissa D. Boersma
11:00 AM Synthesis and evaluation of novel chiral aaAAs as b-sheet stabilizing factors
Jia Wang, Robert P. Hammer
11:20 AM In vitro synthesis of lantibiotic analogs
Champak Chatterjee, Lili Xie, Yong L. Leung, Wilfred A. van der Donk
11:40 AM Investigations of the cyclase enzymes involved in lantibiotic biosynthesis
Moushumi Paul, Wilfred A. van der Donk

Symposium Grid -- Division of Organic Chemistry -- Session Listing

The 228th ACS National Meeting, in Philadelphia, PA, August 22-26, 2004