ORGN 591 |
| Bryan Branstetter and M. Mahmun Hossain. University of Wisconsin-Milwaukee, 3210 N. Cramer Street, Milwaukee, WI 53211 |
| Our group has discovered that HBF4•OEt2 can catalyze the reaction between aromatic aldehydes and ethyl diazoacetate to produce β-hydroxy acrylates and β-keto esters in good yields. To further advance this idea we shifted our attention to the more unreactive aromatic, cyclic, and aliphatic ketones, to investigate if they to will produce the desired β-hydroxy acrylates in good yield. Our group is currently interested in acrylates because we feel they have potential for further downstream synthesis of important biologically active compounds. |
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New Reactions, Methodology, Heterocycles, Aromatics
8:00 PM-10:00 PM, Wednesday, August 25, 2004 Pennsylvania Convention Center -- Hall D, Poster
Division of Organic Chemistry |