Development and application of amplified fluorescent chemosensors

ORGN 350

Steven J. Broadwater and D. Tyler McQuade. Department of Chemistry and Chemical Biology, Cornell University, Baker Laboratory, Ithaca, NY 14853-1301
We have previously reported the construction and characterization of a donor-acceptor based fluorescent chemosensor. The responsive component in this system is a small molecule dye that undergoes a red-shift in absorption and emission following interaction with acid. This signal is then amplified via energy transfer from the bulk donor phase to the protonated acceptor. Current research efforts are focused on coupling this highly sensitive sensory platform to recognition elements that allow for specific detection of a wide range of analytes. The bulk of this talk will discuss design, synthesis, and characterization of recognition elements we have designed to couple to our films.

 

Materials, Devices, and Switches
1:00 PM-5:00 PM, Tuesday, August 24, 2004 Pennsylvania Convention Center -- 201B, Oral

Division of Organic Chemistry

The 228th ACS National Meeting, in Philadelphia, PA, August 22-26, 2004