ORGN 797 |
Polymer-supported metal scavengers and their applications in modern synthesis
| Paul A Boguszewski1, Andrew F Coffey1, John W Davies1, Alasdair A MacDonald2, Aubrey J Mendonca2, and Frank P Warner1. (1) Polymer Laboratories Ltd, Essex Road, Church Stretton, Shropshire, SY6 6AX, United Kingdom, (2) Polymer Laboratories Inc, Amherst Fields Research Park, 160 Old Farm Road, Amherst, MA 01002 |
| The range of reliable organometallic reactions has increased greatly over the last few decades and it is commonplace to see such reactions in a high throughput chemistry environment. The removal of metals such as palladium, tin, lead, iron, cobalt, nickel and copper from organic reactions and samples is therefore essential to provide clean, screenable compounds for synthetic organic and medicinal chemistry. Herein, we describe several polymer supported metal scavengers, which effectively remove a variety of metals from organic solutions without the need for silica or other chromatography products. 
|
| |
|
Combinatorial, Parallel, and Solid-Phase Chemistry
1:00 PM-5:00 PM, Thursday, August 26, 2004 Pennsylvania Convention Center -- 202B, Oral
Division of Organic Chemistry
The 228th ACS National Meeting, in Philadelphia, PA, August 22-26, 2004
|