ORGN 242 |
| Timothy M. Swager, Department of Chemistry and Institute for Soldier Nanotechnologies, Department of Chemistry and Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, Cambridge, MA 02139 |
| This presentation will describe the design of electronic polymers that have the ability to undergo self-amplified responses. Optimal energy and charge transport properties are key to the amplifying ability of these materials. In this process electronic polymers interconnect receptor or binding sites that interact with specific analytes. By wiring receptors in series with a conjugated polymer, the activation of only a small fraction of the receptors by a target analyte results in a substantial reduction in the overall signal. In this way sensory schemes have been devised with unprecedented sensitivity. Design principles have been developed that can be used to improve the mobility and lifetime of excitons will be presented. To elicit a selective sensor response different molecular recognition principles have been integrated into the polymers. Effective implementation of recognition elements requires effective transduction events that are compatible with the amplifying ability of the polymers. Designs based upon energy transfer, quenching, and excimer formation will be presented for the detection of DNA, proteins, chemical warfare agents, explosives, cations, and anions. |
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Tetrahedron Prize for Creativity in Organic Chemistry
1:00 PM-5:10 PM, Monday, August 23, 2004 Pennsylvania Convention Center -- Ballroom B, Oral
Division of Organic Chemistry |