ORGN 120 |
De-novo synthesis of branched and linear mixed D/L oligosaccharides
| Satheesh Babu Ravula, Maoquan Zhou, and George A. O'Doherty. C. Eugene Bennett Department of Chemistry, West Virginia University, 284 Prospect Street, 217 Clark Hall of Chemistry, WVU, Morgantown, WV 26506 |
| The 1,4 and/or 1,6 branched and linear trisaccharides can be synthesized using a palladium catalyzed glycosylation reaction. The pyranoses can be in either D or L forms. Key to the overall efficiency of this process is the use of diastereoselective reductions and dihydroxylations in tandem. Total 15 stereocenters of the complex structures can be achieved in 9 steps from furan ketone. 
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Asymmetric Reactions and Syntheses, Metal-Mediated Reactions, Materials, Molecular Recognition
8:00 PM-10:00 PM, Sunday, August 22, 2004 Pennsylvania Convention Center -- Hall D, Poster
Division of Organic Chemistry
The 228th ACS National Meeting, in Philadelphia, PA, August 22-26, 2004
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