ORGN 601 |
Facile synthesis and purification of 1-acyldipyrromethanes
| Muthukumaran Kannan, Marcin Ptaszek, and Jonathan S. Lindsey. Department of Chemistry, North Carolina State University, Raleigh, NC 27695-8204 |
| 1-Acyldipyrromethanes (1) are important precursors in the synthesis of trans-A2B2, trans-AB2C, cis-A2B2, cis-AB2C, and ABCD porphyrins. 1-Acyldipyrromethanes streak upon chromatography and give amorphous powders upon attempted crystallization, thereby requiring lengthy chromatography for purification. We have developed a refined synthesis that sidesteps such handling problems and affords multigram quantities of 1-acyldipyrromethanes in a simple manner. 
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New Reactions, Methodology, Heterocycles, Aromatics
8:00 PM-10:00 PM, Wednesday, August 25, 2004 Pennsylvania Convention Center -- Hall D, Poster
Division of Organic Chemistry
The 228th ACS National Meeting, in Philadelphia, PA, August 22-26, 2004
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