ORGN 131 |
| Narayan G. Bhat, Chemistry, Chemistry, University of Texas-Pan American, 1201 West University Drive, Edinburg, TX 78541 |
| A convenient, novel synthesis of (E)-gem-dimetalloakenes containing boron and germanium from the Z-1-bromo-1-alkenylboronate esters is developed. Alpha-bromo- (Z)-1-alkenylboronate esters readily prepared from the literature procedures smoothly undergo a reaction with freshly generated trimethylgermyllithium in hexamethylphosphoramide (HMPA) at -78oC to provide the corresponding tetracoordinated boron complexes. These tetracoordinated boron complexes undergo intramolecular nucleophilic substitution reaction to provide the corresponding (E)-1-alkenylboronate esters containing trimethylgermyl moiety. These intermediates are isolated in good yields (72%-81%) and are characterized by the spectral data (PMR and CMR). |
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Asymmetric Reactions and Syntheses, Metal-Mediated Reactions, Materials, Molecular Recognition
8:00 PM-10:00 PM, Sunday, August 22, 2004 Pennsylvania Convention Center -- Hall D, Poster
Division of Organic Chemistry |