CHED 835 |
| Brian C. Veety and Laura J. Anna. Department of Chemistry, Millersville University, 50 E. Fredrick Street, Millersville, PA 17551 |
| Several di-substituted aromatic compounds were nitrated using electrophilic aromatic substitution conditions to examine the directing effects of different groups. Starting materials were chosen in order to look at various competitions between types of directing groups and their activating properties. Using NMR spectroscopy and GC-MS, a ratio of products was determined from each reaction. Molecular modeling calculations of the lowest energy intermediate of each reaction were used to predict the major site of nitration. These results could be used to develop a laboratory experiment for an organic chemistry course to examine competitive effects between directing groups in electrophilic aromatic substitution reactions. |
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Undergraduate Research Poster Session: Organic Chemistry
2:00 PM-4:00 PM, Monday, March 29, 2004 Anaheim Convention Center -- Hall A, Poster
Division of Chemical Education |