CHED 827 |
| Gil Belofsky and Roberto Carreno. Department of Chemistry and Biochemistry, The University of Tulsa, 600 S. College Ave., Tulsa, OK 74104-3189 |
| Our laboratory is currently investigating higher plants of the Southwest as sources of new compounds with biological activity. In our previous work, the genus Dalea has been identified as a rich source of compounds with varying activities. Members of this genus typically progress from herbs in the Eastern United States, to shrubs in the West. Dalea spinosa, the "smoke tree" grows up to 25 feet in height and is the largest member of this genus. Extraction and chromatography of D. spinosa, collected in the Anza-Borrego Desert of California, has resulted in the isolation of several phenolic compounds. Our methods of purification consisted primarily of open column chromatography, with the guidance of thin layer chromatography and NMR spectroscopy. Structural features of the compounds present in the extracts were determined by NMR spectroscopy and mass spectrometry. Details of this work will described in this poster, as well as the results of testing for antibiotic and other biological activities, and the potential uses of the active metabolites. |
|
Undergraduate Research Poster Session: Organic Chemistry
2:00 PM-4:00 PM, Monday, March 29, 2004 Anaheim Convention Center -- Hall A, Poster
Division of Chemical Education |