Stereoselective total synthesis of (-)-vincamajinine and (-)-11-methoxy-17-epi-vincamajine

ORGN 484

Xiangyu Z. Wearing, Jianming Yu, and James M. Cook. Department of Chemistry, University of Wisconsin-Milwaukee, 3210 N. Cramer St., Milwaukee, WI 53201
Recently the total synthesis of (-)-vincamajinine 1 has been achieved. This approach has now been extended to the synthesis of (-)-11-methoxy-17-epi-vincamajine 2. The strategy and key reactions in this approach will be presented.

 

Total Synthesis, Asymmetric Reactions and Syntheses, Bioorganic
9:00 AM-11:00 AM, Wednesday, March 31, 2004 Anaheim Convention Center -- Hall C, Poster

Division of Organic Chemistry

The 227th ACS National Meeting, Anaheim, CA, March 28-April 1, 2004