ORGN 553 |
| Paul A Boguszewski1, Andrew F Coffey1, John W Davies1, Alasdair A MacDonald2, Aubrey J Mendonca3, Mark I Richards1, and Frank P Warner1. (1) Polymer Laboratories Ltd, Essex Road, Church Stretton, Shropshire, SY6 6AX, United Kingdom, (2) Polymer Laboratorie Inc, Amherst Fields Research Park, 160 Old Farm Road, Amherst, MA 01002, (3) Polymer Laboratories Inc, Amherst Fields Research Park, 160 Old Farm Road, Amherst, MA 01002 |
| There are a wide range of polymer supported oxidizing agents and reducing agents commercially available. Frequently these are available as quaternary amine ion exchange resins with an appropriate counter ion. Sadly, the most commonly used ion exchange resin is not particularly well suited to the high performance applications of High Throughput Experimentation. Here we report on the merits of resins produced using a specially engineered base resin designed for drug discovery applications with representative reduction and oxidation transformations. |
|
Combinatorial, parallel, and solid-phase chemistry
1:00 PM-5:00 PM, Wednesday, March 31, 2004 Anaheim Convention Center -- 303A, Oral
Division of Organic Chemistry |