ORGN 421 |
| Joshua Roth, Department of Chemistry, Univeristy of California, Irvine, 516 Roland Hall, Irvine, CA 92697 and A. R. Chamberlin, Department of Chemistry, University of California at Irvine, Irvine, CA 92697. |
| Studies directed toward the synthesis of Correolide, a selective small molecule inhibitor of the KV1.3 ion channel, employing a diastereoselective Diels–Alder reaction are described. Our work on convergent strategies that utilize an intramolecular Heck reaction to construct a tetracyclic core is also outlined. |
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Total Synthesis, Asymmetric Reactions and Syntheses, Bioorganic
9:00 AM-11:00 AM, Wednesday, March 31, 2004 Anaheim Convention Center -- Hall C, Poster
Division of Organic Chemistry |