Enantioselective molecular recognition between b-sheets

ORGN 359

De Michael Chung and James S. Nowick. Department of Chemistry, University of California, Irvine, Irvine, CA 92697
This paper demonstrates that molecular recognition between b-sheets is highly enantioselective. 1H NMR studies of pairings of peptide model systems in CDCl3 solution establish that homochiral pairing among antiparallel b-sheets occurs with >96:4 selectivity over heterochiral pairing.

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