Synthetic studies toward SNF4435 C and SNF4435 D

ORGN 430

Christopher M. Beaudry, Department of Chemistry, University of California - Berkeley, Berkeley, CA 94720 and Dirk Trauner, Department of Chemistry, University of Califonia, Berkeley, 602 Latimer Hall, Berkeley, CA 94720-1460.
A synthetic approach toward the immunosuppresants SNF4435 C and SNF4435 D featuring a tandem Stille coupling/electrocylization cascade affording the core of the natural products is described.