Functionalized alkenes from epoxides

ORGN 58

David M. Hodgson and Matthew J. Fleming. Dyson Perrins Laboratory, Oxford University, South Parks Road, Oxford, OX1 3QY, United Kingdom
The formation of alkenes, while controlling the resulting double bond geometry is of central importance in organic chemistry. This work will describe the addition of functionalised organolithiums to epoxides in the presence of an additive resulting in trans-alkenes. In the absence of the additive simple nucleophilic ring opening occurs.

 

New Reactions and Methodology, Metal-Mediated Reactions, Heterocycles and Aromatics
8:00 PM-10:00 PM, Sunday, March 28, 2004 Anaheim Convention Center -- Hall A, Poster

Division of Organic Chemistry

The 227th ACS National Meeting, Anaheim, CA, March 28-April 1, 2004