ORGN 91 |
| Manojit Pal, Karuppasamy Parasuraman, Venkataraman Subramanian, Rambabu Dakarapu, and Koteswar R. Yeleswarapu. Chemistry-Discovery Research, Dr. Reddy’s Laboratories Ltd, Bollaram Road, Miyapur, Hyderabad, 500049, India |
| Sequential palladium catalysis is utilized for the stereo-controlled synthesis of enynes in a simple synthetic operation. A variety of terminal alkynes were reacted with 3-iodo(thio)flavone in the presence of palladium catalyst and a copper salt involving a mild and convenient method which resulted in 3-enynyl and/or alkynyl derivatives of potential biological interest. The mechanism and scope of the reaction will be discussed. |
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New Reactions and Methodology, Metal-Mediated Reactions, Heterocycles and Aromatics
8:00 PM-10:00 PM, Sunday, March 28, 2004 Anaheim Convention Center -- Hall A, Poster
Division of Organic Chemistry |