Concise, protective group-free syntheses of Hamigeran B and 4-Bromohamigeran B

ORGN 427

Edward Piers and Stephen Y. W. Lau. Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada
Short, concise and protective group-free syntheses of (±)-Hamigeran B and (±)-4-Bromohamigeran B are presented. The key reactions include an enone migration, and a Diels-Alder cyclization to form the requisite tricyclic skeleton.

 

Total Synthesis, Asymmetric Reactions and Syntheses, Bioorganic
9:00 AM-11:00 AM, Wednesday, March 31, 2004 Anaheim Convention Center -- Hall C, Poster

Sci-Mix
8:00 PM-10:00 PM, Monday, March 29, 2004 Anaheim Convention Center -- Hall A, Sci-Mix

Division of Organic Chemistry

The 227th ACS National Meeting, Anaheim, CA, March 28-April 1, 2004