ORGN 492 |
| James S. Nowick, Omid Khakshoor, Mehrnoosh Hashemzadeh, and Justin O. Brower. Department of Chemistry, University of California, Irvine, 4126 Natural Sciences 1, Irvine, CA 92697-2025 |
| The widely used internal standard for NMR studies in aqueous solution DSS (sodium 4,4-dimethyl-4-silapentane-1-sulfonate) can interact with cationic peptides, diminishing its value for such studies. This paper describes DSA (4,4-dimethyl-4-silapentane-1-ammonium trifluoroacetate) as a new internal standard that does not suffer from this problem. Examples of the superiority of DSA from our recent publication [Org. Lett. 2003, 5, 3511-3513] and additional examples will be presented. Free samples of DSA are available to principal investigators upon request by e-mail to jsnowick@uci.edu. |
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Total Synthesis, Asymmetric Reactions and Syntheses, Bioorganic
9:00 AM-11:00 AM, Wednesday, March 31, 2004 Anaheim Convention Center -- Hall C, Poster
Division of Organic Chemistry |
