Investigation of transition metal-mediated supramolecular self-assemblies featuring endohedral ethylenediamine palladium (II) moieties

ORGN 384

Zachary L. Mensinger1, Ronald G. Brisbois1, Heidi L. Erickson1, Marc D. Rodwogin1, Tendai L. Gadzikwa1, Carlos G. Alfonzo1, Christopher J. Markworth2, Nhut K. Diep2, and Paul A. Grieco2. (1) Department of Chemistry, Macalester College, 1600 Grand Ave., St. Paul, MN 55105, (2) Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717

As part of an ongoing collaboration focused on transition metal-mediated supramolecular self-assembly, we have applied the (en)Pd (II) moiety to the formation of a variety of macrocyclic and cage complexes. In these assemblies, the ethylenediamine blocking ligands are located on the outside with respect to the macrocycle or cage interior (i.e. exohedral). To the best of our knowledge, all reported applications of the (en)Pd (II) moiety for directing self-assembly also result in exo positioning of the ethylenediamine blocking ligands. To establish a structural complement to our own work and that of others, we have synthesized a series of ligands (1-3) featuring a preorganized topology expected to incorporate (en)Pd (II) moieties such that the blocking ligands are positioned within the macrocycle or cage interior (i.e. endohedral). The successful formation of such endo self-assemblies will be presented.

Physical Organic, Combinatorial, Materials, Molecular Recognition 8:00 PM-10:00 PM, Tuesday, March 30, 2004 Anaheim Convention Center -- Hall A, Poster Division of Organic Chemistry The 227th ACS National Meeting, Anaheim, CA, March 28-April 1, 2004