ORGNSunday, September 7, 2003

1:00 PM-5:00 PM Sheraton New York -- Royal Ballroom B,Oral
Process R&D
Presiding:J. Christopher McWilliams
1:00 PM 73Practical synthesis of the new carbapenem antibiotic ertapenem sodium
J. M. Williams, K. M. J. Brands, K. M. Conrad, B. Pipik, K. A. Savary, F-R. Tsay, P. G. Houghton, R. T. Skerlj, R. B. Jobson, G. Marchesini, L. M. DiMichele, U-H. Dolling
1:20 PM 74Enantio- and regioselective opening of 2-alkyl nosylaziridines by indoles mediated by boron trifluoride. Application to a practical synthesis of a GnRH antagonist
Roger N. Farr, Ramon J. Alabaster, John Y. L. Chung, Bridgette Craig, John S. Edwards, Andrew W. Gibson, Guo-Jie Ho, Guy R. Humphrey, Simon A. Johnson, Edward J. J. Grabowski
1:40 PM 75A general approach to 2-substituted indoles
Jacqueline H. Smitrovich, Chuanxing Qu, Ian W. Davies, Dave Hughes
2:00 PM 76Process development in the preparation of substituted oxazoles
Kenneth J. Natalie, Andrew Rusowicz, Dale J. Vanyo, Raymond E. Weaver, Ambarish K. Singh
2:20 PM 77Practical synthesis of a 5-aryl-1,3-thiazolidine-2,4-dione PPAR agonist
Michael H. Kress, M. David Weingarten, Christopher J. Welch, Maria Beconi, David J. Mathre, James M. McNamara
2:40 PM 78Synthesis of a dual PPAR agonist and the formation of a sterically congested alpha-aryloxyisobutyric acid
Raymond J. Cvetovich, John Y. L. Chung, Michael H. Kress, Joseph S. Amato, George Zhou, Louis Matty, F.R. Tsay, Zhen Li
3:00 PM 79Development of the synthesis of BMS-250749, a potent topoisomerase inhibitor
Jianji Wang, Miguel Rosigana, Daniel Watson, Eric Dowdy, Meena Rao, Robert Discordia, Nachimuthu Soundarajan, Wen-Sen Li
3:20 PM 80Chromatography in support of pharmaceutical process research
Christopher J. Welch
3:40 PM 81A convenient one-pot synthesis of 1,8-naphthyridones
Shawn A. Springfield, Karen Marcantonio, Scott Ceglia, Jennifer Albaneze-Walker, Peter G. Dormer, Todd D. Nelson, Jerry A. Murry
4:00 PM 82Practical process solutions for Suzuki coupling reactions
Atul S. Kotnis, Kenneth J. Natalie, Bruce Lotz, Ambarish K. Singh, Raymond E. Weaver, David Kascur, David Thurston, Keming Zhu, J. Siva Prasad
4:20 PM 83Palladium mediated Ferrier rearrangement type glycosidation with aromatization prone xylo-furanoid glycals for the synthesis of biologically active nucleosides
Anusuya Choudhury, Michael E. Pierce, Dieu Nguyen, Louis Storace, Pat Confalone
4:40 PM 84Synthesis of an alpha-alkylamino pyrazinone thrombin inhibitor mediated by 2-pyridylthioimidate-ZnCl2 complexes
Raymond J. Cvetovich, John Y. L. Chung, Fuh-Rong Tsay, Peter G. Dormer, Lisa DiMichele, Bing Mao, Robert Wenslow

Symposium Grid -- Division of Organic Chemistry -- Session Listing

The 226th ACS National Meeting, New York, NY, September 7-11, 2003