ORGNWednesday, September 10, 2003

11:00 AM-1:00 PM Javits Convention Center -- Hall 1B/1C,Poster
Bioorganic, Molecular Recognition, Asymmetric Reactions and Syntheses
Organizer:L. McElwee-White
500A novel dynamic kinetic asymmetric transformation concept employing a ruthenium epimerization catalyst together with an enzyme
Michaela Edin, Johannes Steinreiber, Jan-E. Bäckvall
501Rapid synthesis of a series of novel polyhydroxylated, fused, bicyclic heterocyclic analogs and their activities against human mannosidases
Udayan Das, Heather Strachan, Kelley Moremen, Aloysius Siriwardena
502Novel diaminopyrimidine inhibitors of c-Jun N-terminal kinase 3 (JNK3) :- SAR and ligand co-crystallization studies
Vu Ma, Paul A. Tempest, Liping Pettus, Janan Jona, Charles Henley, Sekhar Surapaneni, Ella Magal, David Powers, Yan-yan Xie, Chris Mohr, Yax Sun, Steve Jordan, Bill Harte, Randall Hungate, Christopher Hulme, Jim Meyer
503Synthesis of DNA single strand-containing 15N labeled cis-syn thymine dimer
Hussam M. Bdour, John-Stephen A. Taylor
504Synthesis of redox switchable reverse recognition molecular muscles
Paul A. Bonvallet, Fraser Stoddart
505Amino acids bridged to quinones and to bisquinonyl isocyanurates
Julia Ditkovich, Galina Temtsin-Krayz, Eli Har-Lev, Shmuel Bittner
506Versatile approach to chiral macrocycles
Nello Mainolfi, Susan E. Gibson, S. Barret Kalindjian, Paul T. Wright
507Novel optimized process for large scale preparation of D-erythro-sphingosine 1-phosphate
Zdzislaw M. Szulc, Yusuf A. Hannun, Alicja Bielawska
508Synthesis and conductance study of trans-1,2-cyclopentane dicarboxamide linked Gramicidin-A dimers
David Crumrine, Shasikala Narayan, Samuel Cukierman, Courtney Williams
509Synthesis of 15N-enriched pseudouridine and derivatives
Jean-Paul Desaulniers, Helen Mei-Ping Chui, Christine S. Chow
510Synthesis and DNA/RNA binding properties of conformationally restricted pyrrolidine-amide oligonucleotide mimics (POM)
Anila I. Khan, Samuel T. H. Tan, Jordi Moral-Cardoner, Jason Micklefield
511Synthesis of enantiomeric pure phosphoroselenoate DNA and RNA for structure determination by X-ray crystallography
Zhen Huang, Nicolas Carrasco
512Synthesis of the phosphoramidite derivatives of 2'-deoxy-2'-C-alpha-methylcytidine and 2'-deoxy-2'-C-alpha-hydroxymethylcytidine
Nan-Sheng Li, Joseph A. Piccirilli
513Using designed peptides to study the nature of carbohydrate-protein interactions
Marcey L. Waters, Sarah E. Kiehna
514Small molecule-RNA interactions
Zhaohui Yan, Anne M. Baranger
515Synthesis of fluorophenyl ribonucleosides and their substitution into the U1A-U1snRNA complex
Anne M. Baranger, Yulianingsih Benitex
516Reliable synthesis of aryl c-2-deoxyribosides from inexpensive starting materials
Erik Stolarzewicz, Kathlyn A. Parker
517Retinal binding studies of a rhodopsin protein mimic
Chrysoula Vasileiou, Rachael Crist, Montserrat Rabago-Smith, Babak Borhan
518Engineering a rhodopsin protein mimic
Rachael M. Crist, Chrysoula Vasileiou, Courtney Olmsted, Erika Mathes, Soheila Vaezeslami, James H Geiger, Babak Borhan
519Mechanistic studies of enzymatic catalysis of an intermolecular Aldol reaction: Quantum mechanical and molecular mechanical calculations of the DERA-catalyzed Aldol reaction
Xiyun Zhang, K. N. Houk
520Novel synthesis of a pentadentate ligand for designing protein-based artificial enzyme mimics
Priya P. Joshi, David M. Weber, Christin T. Choma
521@-Tide peptidomimetics in water: Quantification of amino acid side chain-side chain interactions and amino acid conformational preferences in small, stabilized b-hairpins
Scott T. Phillips, Paul A. Bartlett
522Effect of side chains on turns and helices in b3-Aminoxy peptides
Yu-Hui Zhang, Dan Yang
523Novel secondary structure induced by peptides composed of alternating a-L-Aminoxy acids and a-L-Amino acids
Wei Li, Dan Yang, Tze-Wai Kan
524Regioselectivities of intramolecular oxidation of C-H bonds by dioxiranes
Nga-Wai Chung, Dan Yang, Man Kin Wong
525Crosslinked hemoglobin-dye conjugates for photodynamic therapy
David S. Crumrine, Claudia M. Davila, Kenneth Olsen
526Paper Withdrawn
527Strategies for synthesis of nucleoside cyclic boranophosphates and boranophosphorothioates
Ping Li, Kaizhang He, Barbara R. Shaw
528A general approach for the stabilization of peptide secondary structures
Gianluca Dimartino, Ross Chapman, Nicholas G. Angelo, Paramjit S. Arora
529Design and synthesis of artificial carbohydrates based on rigid polyproline scaffolds
Deyun Wang, Ryan J. Casey, Paramjit S. Arora
530Convenient asymmetric synthesis of ß-substituted a,a-difluoro-ß-amino acids via Reformatsky Reaction between N-sulfinylimines and ethyl bromodifluoroacetate
Alexander Sorochinsky, Dmitrii O. Berbasov, Vadim A. Soloshonok
531Synthesis of a high-affinity PPARgamma ligand for high-throughput fluorescence polarization assays
Michael J. DeGrazia, Jerry Thompson, John P. Vanden Heuvel, Blake R. Peterson
532Improved synthesis of proline-derived Ni(II)-complexes of glycine, versatile chiral equivalents of nucleophilic glycine for general asymmetric synthesis of a-amino acids
Tomas U. Boettiger, Shawna B. Bolene, Hisanori Ueki, Trevor K. Ellis, Collin H. Martin, Vadim A. Soloshonok
533Synthesis of chemically modified thiopeptide antibiotics
Adrian P. Revington, Philip A.S. Lowden
534Structure, biosynthetic origin and engineered biosynthesis of Calcium Dependent Antibiotic from Streptomyces coelicolor
Claire E. Milne, Zohreh Hojati, Lyndsey Gordon, John Jim, Gabriel Uguru, Colin P. Smith, Jason Micklefield
535Sulfoximidoyl-oligomers and pseudopeptides: Synthesis, structure and function
Christian P.R. Hackenberger, Dirk Müller, Carsten Bolm
536Synthesis and application of novel fluorometric substrates for caspase-3/7
Zhi-Qiang Wang, Jinfang Liao, Zhenjun Diwu
537Use of site-selective gentamicin derivative in ROCHE-TDM ONLINE Gentamicin Immunoassay
Mitali Ghoshal, Gerald Sigler, Jane Tsai, Ruth Gerbig, Lili Arabshahi, MyLe Hoang, Andrew Schamerloh, Salvatore J. Salamone, Joseph Passarelli
538Solid-phase synthesis of metal chelating lipids
Suad Nadi, Sanku Mallik
539Photolabile lipids based on dithiane-carbonyl adducts: toward light-sensitive liposomes
Andrei G. Kutateladze, Zaiguo Li
540Total synthesis and in vivo identification of eicosapentaenoic acid and docosahexanenoic acid-derived Group VI isoprostanes
Seongjin Kim, Joshua Rokach, John A. Lawson, Garret A. FitzGerald
541Photoactivatable analogues of sphingosine-1-phosphate: synthesis and binding to protein targets
Xuequan Lu, Sandor Cseh, Daniel L Baker, Hoe-Sup Byun, Gabor Tigyi, Robert Bittman
542Synthesis and antiproliferative properties of novel unnatural ceramide analogues
Robert Bittman, Jiong Chun, Hoe-Sup Byun, Gilbert Arthur
543Biosynthesis of the naphthoate fragment of azinomycin B
Christophe Corre, Cyrille A.S. Landreau, Michael Shipman, Philip A.S. Lowden
544Crosslinking of synthetic cell surface receptors by protein ligands triggers endocytosis mediated by lipid rafts
Siwarutt Boonyarattanakalin, Scott E Martin, Blake R. Peterson
545Design, synthesis, and characterization of potential bivalent ligands for histamine receptors
Keith R. Buszek, Paul W. Baures, Om P. Malik
546Mechanistic insights into the oxidative fragmentation of linoleic acid
Ana C. Mesaros, Mingjiang Sun, Robert G Salomon
547Paper Withdrawn
548Biomimetic acyl transfer catalysts
Ahamindra Jain, Sarah M. Vespremi, Gregory K. Pang, Thomas S.-C. Ng
549Enzyme catalytic stability in organic solvents
Gabriel Barletta, Amaris Ferrer, Marc D. Legault
550New cembrane diterpenes from the Caribbean Gorgonian coral Eunicea spp
Xiaomei Wei, Abimael D. Rodríguez
551Synthesis of carbohydrate mimics via ruthenium-based carbenoid catalysis
Jared L. Piper, Maarten H.D. Postema
552Generation, total syntheses, and identification of biologically active oxidized ethanolamine phospholipids
Bogdan G. Gugiu, Mingjiang Sun, Robert G Salomon
553Modifications around the carboxylate group of the tryptophanyl tRNA synthetase inhibitor Chuangxinmycin: Active non-charged analogues and tight sterical constraints
Dieter W. Hamprecht, Murray J B Brown, Martin J. Hibbs, Richard L. Jarvest, Lucy Mensah, Peter J. O'Hanlon, Andrew J. Pope, Christine M. Richardson
554Synthesis of analogues of lycoperdic acid to probe glutamate receptors in the central nervous system
William R. F. Goundry, Victor Lee, Jack E. Baldwin
555A five-membered ring analog of 5-enolpyruvylshikimate-3-phosphate
Ming An, Paul A. Bartlett
556Synthesis of cardiolipin analogues using phosphoramidite approach
Murali K Ukkalam, Moghis U Ahmad, Imran Ahmad
557Cationic cardiolipin analogues for the optimal delivery of therapeutic agents
Krishnudu Kasireddy, Moghis U Ahmad, Imran Ahmad
558Self-assembled light harvesting arrays
Kannan Muthukumaran, Lianhe Yu, Igor Sazanovich, Eve Hindin, Christine Kirmaier, James R. Diers, David F. Bocian, Dewey Holten, Jonathan S. Lindsey
559Sensing strong acids using anthraquinone-polyether luminescence hosts
Andrew G. Sykes, Mariappan Kadarkaraisamy
560Solid phase synthesis of N-substituted glycine oligomers containing nitroxide radical spin-probes
Aaron T Fafarman, Kent Kirshenbaum
561Synthesis and assembly studies of a novel guanosine-cytidine dinucleotide
Jonathan L. Sessler, Janarthanan Jayawickramarajah, Muhunthan Sathiosatham
562Temperature-dependent self-complexing behavior of tethered cyclophanes in solution
Yi Liu, J. Fraser Stoddart
563Preparation of liquid crystals and organogelators with a bitropone core
Kanji Kubo, Akira Mori, Seiji Ujiie, Carsten Tschierske
564Pyrazoles as anion receptors
Jonathan L. Sessler, Bobbi Rubin, Salvatore Camiolo, Won-Seob Cho, Vincent Lynch
565Pyrazine analogues of dipyrrolylquinoxalines: Synthesis, anion binding properties and incorporation in macrocycles
G. Dan Pantos, Jonathan L. Sessler, Evgeny Katayev, Vincent Lynch
566Rigid chiral tripodal ligands as chiroptical metal sensors: strategies to improve selectivity and efficiency
Zhaohua Dai, Nina Berova, James W. Canary
567Search for novel fluorescent zinc sensors
James W. Canary, Maksim Royzen
568Synthesis of a TPA-based mononuclear zinc protease model
Jing Zhang, Lei Zhu, James W. Canary
569Mimicking ß-sheet assembly in aqueous media: Progress towards the controlled dimerization of peptidic macrocycles
Gregory A. Watkins, Paul A. Bartlett
570Molecular recognition and self-assembly at the monolayer interface
Mark L. Bushey, Colin Nuckolls
571Metal-mediated self-assembling porphyrins for stereochemical determination
Courtney C. Olmsted, Qifei Yang, Babak Borhan
572Chiral self-assembly of zinc porphyrin acid with carboxylic acid derivatives
Qifei Yang, Courtney C. Olmsted, Babak Borhan
573Functionalized fluorophores as a route towards protein-detecting arrays
Laura Baldini, Andrew J Wilson, Jason Hong, Andrew Hamilton
574Radially controlled redox modulated gold nanoparticles
Ali Bayir, Roy Shenhar, S. Q. Alam, Vincent Rotello
575Control of protein structure and function through surface recognition by tailored nanoparticle scaffolds
Rui Hong, Nicholas O. Fischer, Ayush Verma, Catherine McIntosh Goodman, Todd Emrick, Vincent Rotello
576Glutathione-mediated rescue of gold nanoparticle-inhibited beta-galactosidase
Ayush Verma, Joseph M. Simard, Vincent M. Rotello
577Mediation of protein activity using nanoparticle-based receptors
Nicholas O. Fischer, Catherine McIntosh Goodman, Ayush Verma, Joseph M. Simard, D. Joseph Jerry, Vincent M Rotello
578Highly fluorescent organogel from nonfluorescent gelator: Fibrillar self-assembly and fluorescence generation through intermolecular hydrogen bond of oxadiazole-based benzene-1,3,5-tricarboxamide
Sehoon Kim, Seung Yeul Ryu, Jangwon Seo, Soo Young Park, Young-Woon Kim, Oh-Hoon Kwon, Du-Jeon Jang
579Synthesis of modifiers for single-walled carbon nanotubes
Christopher F. Bender, Stephen L. Craig
580Bipyrrole-based new calixpyrrole family members: Calix[n]bipyrroles , calix[2]bipyrrole[2]thiophene, and calix[2]bipyrrole[2]furan
Jonathan L. Sessler, Deqiang An, Won-Seob Cho, Vincent Lynch
581Calixarenes for molecular capsules
Suazette N. Reid, Suzanne B. Shuker
582Paper Withdrawn
583Hexacarboxylic acid biscavitands
Gang Zhao, Linda M. Tunstad, Peter P Castro
584New boronic acid fluorescent reporter compound suitable for saccharide sensing at physiological pH
Xingming Gao, Yanling Zhang, Sabapathy Sankar, Binghe Wang
585Novel bicyclic diketopiperazines as scaffolds for non-covalent self-assembly
Yanming Du, Christopher J. Creighton, Brett A. Tounge, Allen B. Reitz
586Water soluable terphenyl derivatives as mimics of Bak peptide that targets Bcl-xL protein
Hang Yin, Andrew D. Hamilton
587Fluorescent coatings for dopamine detection
Mabel A. Cejas, Francisco M Raymo
588A stereoselective aldol reaction via diisopinocampheyl boron-enolate
Fengrui Lang, Daniel Zewge, Zhiguo J. Song, Mirlinda Biba, Peter Dormer, David Tschaen, R.P. Volante, Paul J. Reider
589Asymmetric total synthesis of carbocyclic sinefungin
Marvin J. Miller, Bohan Jin, Namal C. Warshakoon, Jennifer L. Gage
590Understanding origin of enantioselection without steric reasoning: A general electronic theory for asymmetric induction and kinetic resolution
David Zhigang Wang
591On the equivalence of helicity and chirality: A helical structure-based generalization of molecular asymmetry
David Zhigang Wang
592Synthesis of enantiopure dihydropyranones: Aldol-based ring expansion of dihydrofurans
Graeme C. Freestone, Timothy J. Donohoe
593An exciton coupling circular dichroism approach to solving absolute configuration of 1,n-Diols (n=5,7,9)
John B. MacMillan, Tadeusz F. Molinski
594Synthesis of chiral ortho-substituted BIPHEP ligand and its application in asymmetric hydrogenation
Xumu Zhang, Shulin Wu, Minsheng He
595Synthesis, application and mechanistic study of transition metal complexes with tunable chiral monodentate phosphorous ligands in catalytic asymmetric reactions
Zihao Hua, Victor C. Vassar, Hojae Choi, Iwao Ojima
596New Ru and Rh catalysts for asymmetric transfer hydrogenation
Martin Wills, Jérôme C. B. Hannedouche, Aidan Hayes, Aparecida M Kawamoto, David J Cross
597Paper Withdrawn
598Highly efficient syntheses of polyfunctional lactones and lactams via Rh(I)-catalyzed cycloisomerization
Aiwen Lei, Minsheng He, Jason P. Waldkirch, Xumu Zhang
599Modular assembly and applications of electron-rich phosphine ligands from fluorinated aromatic building blocks
Shahla Yekta, Andrei K. Yudin
600Paper Withdrawn
601Novel sulfinyl imine ligands for asymmetric catalysis
Jonathan A. Ellman, Laurie B. Schenkel
602Organocatalytic asymmetric assembly reactions: Stereochemically complex products assembled by proline and other organocatalysts
Fujie Tanaka, Naidu S. Chowdari, D. B. Ramachary, Shin-ichi Watanabe, Wolfgang Notz, James M. Turner, Carlos F. Barbas III
603Chiroptical features of chiral tripodal metal complexes containing tetraphenylphorphyrin chromophores
Andrea E. Holmes, Debasis Das, James W. Canary
604Exciton-coupled circular dichroism studies of Cu(II) complexes of N,N-bis(2-quinolylmethyl) amino alcohols, ethers, and thioethers
Samuel A. Simpson, Andrea E. Holmes, James W. Canary
605Asymmetric synthesis of aziridine 2-phosphonates from enantiopure sulfinimines (N-Sulfinyl Imines)
Franklin A. Davis, Yongzhong Wu, Tokala Ramachandar
606Asymmetric synthesis of substituted pyrrolidines from N-sulfinyl a-amino a-ketoesters
Franklin A Davis, Jianghe Deng, Bin Yang, Tianan Fang
607a-Aryl quaternary centers via diastereoselective multi-component coupling reactions
Christopher A. Davies, Nicholas J. Lawrence, Matthew Gray
608Asymmetric hydrogenation of olefins catalyzed by Ir-complexes with new phosphine oxazoline ligands
Duan Liu, Wenjun Tang, Xumu Zhang
609Development of novel chiral ferrocenyl-phosphine ligands for asymmetric [3+2] cycloaddition
Xumu Zhang, Malati Raghunath, Bin Wang
610OH - Pd(0) hydrogen bond in palladium-catalyzed allylic alkylation
Anders Frölander, Tebikie Wondimagegn, Kristina Hallman, Mats Svensson, Christina Moberg
611Stereoselective total synthesis of (-)-Bulgecinine
Juhienah K. Khalaf, Apurba Datta
612Toward the asymmetric total synthesis of fusicoccin A
Vyjayanthi N. Kambam, Scott McN. Sieburth
613Asymmetric synthesis and use of amine-substituted allylsilanes
Guodong Liu, Scott McN. Sieburth
614Asymmetric synthesis of fluorobicycloketones
Audrey Wong, Jeffrey T Kuethe, Ian W. Davies, David L. Hughes, Rich Tillyer
615Asymmetric synthesis of novel trifluoromethyl substituted epinephrine derivatives
Jeffrey R. Ammann, Michael Crowe, Jonathan West
616Polyene cyclization using ring closing metathesis reactions: Applications to the asymmetric total synthesis of Oximidine I and II
Jossian Oppenheimer, Robert S. Coleman
617Pseudoephedrine as a chiral auxiliary for asymmetric Michael reactions: synthesis of 3-aryl-d-lactones
Geneviève N. Boice, Jacquiline Smitrovich, Chuanxing Qu, Lisa DiMichele, Todd D. Nelson, Mark A. Huffman, Jerry Murry, McNamara James, Paul J. Reider
618Asymmetric aldol type reactions of carboxylic esters using MgI2 as promoter
Han-Xun Wei, Paul W. Pare
619Stereoselective synthesis of a,b-substituted-b-mercaptocarboxylic acid derivatives: Asymmetric 1,4-addition using C2-symmetric pyrrolidine derivatives (II)
Young Gyu Kim, Dong Hwal Lee, Jae Kwang Hwang, Hee Bong Lee, Byung Hyun Kim
620Catalytic asymmetric [3+2] cycloaddition of hydrazones with olefins
Yasuhiro Yamashita, Haruka Shimizu, Haruro Ishitani, Shu Kobayashi
621Stereoselective intramolecular aza [ 3 + 3 ] formal cycloaddition approach to Indolizidines and Quinolizidines
Richard P. Hsung, Heather Coverdale, Xiao-Fang Yang, Lin-Li Wei, Aleksey I. Gerasyuto
622Synthesis of chiral ß-amino esters and amides via a highly diastereoselective hydrogenation of chiral enamines
Norihiro Ikemoto, David M. Tellers, Nelo Rivera, Spencer D. Dreher, Jinchu Liu, Eugenia Njolito, Angie Huang, Yi Hsiao, J. Christopher McWilliams, J. Michael Williams, Yongkui Sun, Joseph D. Armstrong, David J. Mathre, Edward J. J. Grabowski
623Pseudoephedrine amide enolates in asymmetric Michael reactions: Effect of LiCl on stereoselectivity
Chuanxing Qu, Jacquiline Smitrovich, Lisa DiMichele, Geneviève N. Boice
624Stereoselective synthesis of polyhydroxyl surfactants and investigation of the influence of absolute configuration on surface chemical behavior
Peter Somfai, Kristina Neimert-Andersson
625Catalytic enantioselective domino reactions of acylsilanes
David A. Nicewicz, Jeffrey S. Johnson
626New axially dissymmetric ligand recoverable by fluorous solvent
Itsumaro Kumadaki, Masaaki Omote, Kazuyuki Sato, Akira Ando
627Toward the total synthesis of ionomycin
Martin Allan, Claude Spino
628An asymmetric synthesis of erythro-1,2-diphenyl-1,2-propanediamine
Alexandre C. Gross, Patrick W. Shum, Dirk Friedrich, Neville L. Holder, Jeffrey S. Sabol

Symposium Grid -- Division of Organic Chemistry -- Session Listing

The 226th ACS National Meeting, New York, NY, September 7-11, 2003