MEDIMonday, September 8, 2003

1:30 PM-5:10 PM Sheraton New York -- Royal Ballroom A,Oral
Role of Organic Synthesis in Early Clinical Drug Development
Organizer, Presiding:Stephane Caron
1:30 PM 36Introductory Remarks: Recent changes in early development environment
Stephane Caron
1:40 PM 37Development and optimization of the asymmetric synthesis of ABT-100
Albert W. Kruger, Michael J. Rozema, Bridget D. Rohde, James Jien-Heh Tien, Weijiang Zhang, Lakshmi Bhagavatula, Bhadra Shelat
2:20 PM 38Practical synthesis of cell adhesion inhibitors via crystallization-driven dynamic transformations
Nathan K. Yee, Magnus Eriksson, Vittorio Farina, Rogelio P. Frutos, Suresh Kapadia, Elio Napolitano
3:00 PM 39Large-scale synthesis of cryptophycin 52 (LY355703)
James A. Aikins, Tony Zhang, Takia Oglesby
3:40 PM 40Asymmetric hydrogenation: A new process to Pregabalin
William S. Kissel
4:20 PM 41Development of carbo- and heterocyclizations: Application to a practical synthesis of the Cox-II specific inhibitor Etoricoxib
Jean-Francois Marcoux

Symposium Grid -- Division of Medicinal Chemistry -- Session Listing

The 226th ACS National Meeting, New York, NY, September 7-11, 2003