Process development in the preparation of substituted oxazoles

ORGN 76

Kenneth J. Natalie, Andrew Rusowicz, Dale J. Vanyo, Raymond E. Weaver, and Ambarish K. Singh. Process Research and Development, Bristol-Myers Squibb Pharmaceutical Research Institute, One Squibb Drive, P. O. Box 191, New Brunswick, NJ 08903-0191
This talk will cover process development issues to prepare substituted oxazoles in two steps from readily available aryl benzoyl halides. Safe handling of Eaton's reagent on-scale will be discussed.
 

Process R&D
1:00 PM-5:00 PM, Sunday, September 7, 2003 Sheraton New York -- Royal Ballroom B, Oral

Division of Organic Chemistry
The 226th ACS National Meeting, New York, NY, September 7-11, 2003