New approaches to enantioselective synthesis through catalytic asymmetric olefin metathesis

ORGN 8

Jesper A. Jernelius, Department of Chemistry, Boston College, Merkert Chemistry Center, Chestnut Hill, MA 02467, Amir H. Hoveyda, Department of Chemistry, Merkert Chemistry Center, Boston College, 2609 Beacon St., Chestnut Hill, MA 02467, and Richard R. Schrock, Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Room 6-331, Cambridge, MA 02139.
Recent studies in the design and development of new asymmetric catalytic reactions will be presented. Advances in the area of enantioselective catalytic olefin metathesis will be emphasized. The utility of asymmetric catalytic ring-closing metathesis (ARCM), especially when used in combination with cross-metathesis processes will be disclosed. Mechanistic implications of our findings, and the effect of the modification of modular chiral ligands on reactivity and selectivity will be highlighted

 

Asymmetric Reactions and Syntheses
8:00 AM-12:00 PM, Sunday, September 7, 2003 Sheraton New York -- Imperial Ballroom A, Oral

Division of Organic Chemistry
The 226th ACS National Meeting, New York, NY, September 7-11, 2003