Reliable synthesis of aryl c-2-deoxyribosides from inexpensive starting materials

ORGN 516

Erik Stolarzewicz and Kathlyn A. Parker. Department of Chemistry, State University of New York at Stony Brook, Stony Brook, NY 11794-3400
Aryl C-2-deoxyribosides may act as universal bases and are useful building blocks for the preparation of versatile nucleic acid probes. We have developed a dependable 9-step synthesis of aryl C-2-deoxyribosides from D-mannitol.