ORGN 452 |
Approaches to catalyzing the cation-olefin multicyclization reaction
| Michel R. Gagné, Jeffrey W. Anthis, Jeong Hwan Koh, Cheryl M. Mascarenhas, and Jeremy Feducia. Department of Chemistry, University of North Carolina at Chapel Hill, CB#3290, Chapel Hill, NC 27599 |
A new family of highly electrophilic late-metal complexes for initiating the cation-olefin multicyclization reaction will be described. A family of palladium and platinum complexes capable of initiating the diastereoselective cyclization of di-ene-ol and di-ene-amide compounds into multicyclic (6.6, and 6.5) structures will be described. Efforts to convert these stoichiometric processes into non-oxidative, catalytic, cyclization reactions will also be described; along with tri- and tetra-ene compounds. An example of the cyclization of a di-ene-ol with a (PNP)Pd2+ catalyst initiator is shown below.  |
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Physical Organic, Materials, Heterocycles, Aromatics, Metal-Mediated Reactions
8:00 PM-10:00 PM, Tuesday, September 9, 2003 Hilton New York -- Americas Hall 1, Poster
Sci-Mix
8:00 PM-10:00 PM, Monday, September 8, 2003 Javits Convention Center -- North Pavillion, Sci-Mix
Division of Organic Chemistry
The 226th ACS National Meeting, New York, NY, September 7-11, 2003
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