ORGN 237 |
Synthesis and properties of octasubstituted phthalocyanine dyes
| Guifa Su, Vera Verdree, Robert P. Hammer, and Steven A. Soper. Dept. of Chemistry, Louisiana State University, 232 Choppin Hall, Baton Rouge, LA 70803 |
Near-IR fluorescence detection technology has many advantages over traditional UV or visible fluorescence methods including lack of native fluors, low cost laser diode excitation sources, and low Raman scattering background. However, there is still a need for chemically robust dyes that absorb and fluoresce in the near-IR. We are currently investigating new water-soluble phthalocyanines (PCs) as labeling reagents for biomolecules. In this presentation, we describe the synthesis of new octasubstituted PC dyes and their metal-complexes. Their absorbance and fluorescence spectra as well as their fluorescence lifetimes have been measured. The effects of metal and substituent position on the physical properties of the dyes will also be discussed. |
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