ORGN 303 |
| E. Keller Barnhardt and Brittany L. Hayes. Life Sciences Division, CEM Corporation, P.O. Box 200, 3100 Smith Farm Road, Matthews, NC 28106 |
| The use of microwave irradiation in organic synthesis has become an increasingly popular topic within the pharmaceutical and academic arenas. Microwaves have become a new energy source that is powerful enough to complete reactions in minutes instead of hours, or even days. Currently, the majority of microwave-assisted reactions are performed at high temperatures and pressures. Reactions run at lower temperatures (T < 35 °C) have not yet been fully exploited. There are many applications, both synthetic and biochemical, that require either ambient temperatures or below. Because microwave irradiation is only a source of kinetic energy, lower temperatures are easily attainable through removal of the resulting thermal energy. Herein, we will discuss the methodology and demonstrate the utility of running low-temperature reactions in a microwave. |
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New Reactions and Methodology
8:00 AM-12:00 PM, Tuesday, September 9, 2003 Sheraton New York -- Royal Ballroom B, Oral
Division of Organic Chemistry |