ORGN 561 |
Synthesis and assembly studies of a novel guanosine-cytidine dinucleotide
| Jonathan L. Sessler, Janarthanan Jayawickramarajah, and Muhunthan Sathiosatham. Department of Chemistry and Biochemistry and Institute of Cellular and Molecular Biology, The University of Texas at Austin, 1 University Station - A5430, Austin, TX 78712 |
In a continuation of our work to assemble supramolecular structures using modified nucleotide analogs, we present the synthesis and assembly studies of a novel guanosine-cytidine dinucleotide 1. This dinucleotide was prepared via, mild, consecutive Stille and Heck cross-coupling reactions. Ensemble I was characterized by ESI-MS, NMR spectroscopies, size exclusion chromatography (SEC), and by vapor pressure osmometry (VPO).  |
| |
|
Bioorganic, Molecular Recognition, Asymmetric Reactions and Syntheses
11:00 AM-1:00 PM, Wednesday, September 10, 2003 Javits Convention Center -- Hall 1B/1C, Poster
Division of Organic Chemistry
The 226th ACS National Meeting, New York, NY, September 7-11, 2003
|