ORGN 675 |
| David G. J. Young, Dongxiang Zeng, and Joseph A. Burlison. Department of Chemistry, University of Tennessee, Knoxville, 353 Buehler Hall, University of Tennessee, Knoxville, TN 37996 |
| The synthesis of an advanced intermediate in the garsubellin class of compounds will be described. In the key event an allene-nitrile oxide cycloaddition delivers the bicyclicc core and reductive cleavage of the resulting isoxazoline using raney Ni/H2 generates the acylated phloroglucinol ring system. |
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Total Synthesis of Complex Molecules
8:00 AM-12:00 PM, Thursday, September 11, 2003 Sheraton New York -- Imperial Ballroom B, Oral
Division of Organic Chemistry |