New transition metal-catalyzed reactions for total synthesis

ORGN 247

Alois Fürstner, Max-Planck-Institut für Kohlenforschung, D-45470 Mülheim/Ruhr, Germany
Preparative and mechanistic studies on metal-catalyzed bond forming reactions will be presented, including alkene and alkyne metathesis, platinum catalyzed skeletal rearrangements, as well as iron-catalyzed cross coupling. Applications of these methods to the total synthesis of natural products of biological significance will demonstrate their preparative scope and practicality.