| K.C. Nicolaou, Department of Chemistry & Biochemistry, Department of Chemistry & Biochemistry, The Scripps Research Institute and the University of California, San Diego, 10550 N. Torrey Pines Road, La Jolla, CA 92037 |
| Following a short personal introduction, in this lecture K. C. Nicolaou will present a retrospective on his research activities in the field of chemical synthesis from the early days of his graduate career in the late 1960s to the present. Although these endeavors span more than three decades, the covered topics are unified by the same underlying themes of synthesis, new synthetic technologies and chemical biology. The total syntheses of natural products whose stories will bring these themes to light in this lecture include, among others, those of the endiandric acids, efrotomycin, amphotericin B, calicheamicin g1I, rapamycin, TaxolTM, the brevetoxins, the epothilones, vancomycin, the CP-molecules, the bisorbicillinoids, everninomicin, the coleophomones, and diazonamide A.  |