ORGN 116 |
| Young Chul Park and Bill J. Baker. Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, BSF 358, Tampa, FL 33620 |
| The yellow pigment from the Antarctic sponge Isodictya erinacea, erebusinone has been implicated in molt inhibition and mortality against an Antarctic crustacean amphipod, perhaps serving as a precursor of a xanthurenic acid analog. Our interest in erebusinone bioactivity led us to develop synthesis, which we have achieved in an overall yield of 44 % involving 7 steps. The detailed synthetic pathway of erebusinone, which was economical and convenient, will be presented. |
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Molecular Recognition, Combinatorial, Bioorganic
8:00 PM-10:00 PM, Sunday, March 23, 2003 Convention Center -- Hall G, Poster
Division of Organic Chemistry |